The GABARAPL1 Polyclonal Antibody (CAB7790) is a valuable tool for researchers studying GABARAPL1, a member of the GABARAP family of proteins that play a role in autophagy. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the GABARAPL1 protein, this antibody enables detection and analysis in a variety of cell types, making it ideal for research in autophagy regulation and its implications in diseases like neurodegeneration and cancer.GABARAPL1 is known to be involved in the process of autophagy, which is essential for maintaining cellular homeostasis by degrading and recycling damaged organelles and proteins.
Dysregulation of autophagy has been implicated in various diseases, including neurodegenerative disorders such as Alzheimer's and Parkinson's.By using the GABARAPL1 Polyclonal Antibody in their research, scientists can gain insights into the function of GABARAPL1 in autophagy and its potential as a therapeutic target for diseases associated with autophagy dysfunction. This antibody provides a valuable tool for understanding the molecular mechanisms underlying autophagy and its role in disease pathogenesis.
Product Name:
GABARAPL1 Rabbit Polyclonal Antibody
SKU:
CAB7790
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-50 of human GABARAPL1 (NP_113600.1).
Enables Tat protein binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in autophagosome assembly; autophagy of mitochondrion; and cellular response to nitrogen starvation. Located in autophagosome. Colocalizes with mitochondrion.
Purification Method:
Affinity purification
Gene ID:
23710
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of Mouse brain, using GABARAPL1 antibody (CAB7790) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
