The GABARAP Rabbit Monoclonal Antibody (CAB4335) is specifically designed for research involving GABARAP, a key protein involved in autophagy and cellular signaling pathways. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting and immunofluorescence.GABARAP, a member of the ATG8 family, plays a crucial role in autophagy, a cellular process that degrades and recycles damaged organelles and proteins. Dysregulation of autophagy has been linked to numerous diseases, including neurodegenerative disorders and cancer.
Studying GABARAP using this antibody can provide valuable insights into the mechanisms of autophagy and its implications in disease pathogenesis.With its high specificity and sensitivity, the GABARAP Rabbit Monoclonal Antibody (CAB4335) is an essential tool for researchers investigating autophagy, cellular homeostasis, and the role of GABARAP in various cellular processes. Its use can contribute to a better understanding of autophagy-related diseases and the development of potential therapeutic interventions targeting the autophagy pathway.
Product Name:
GABARAP Rabbit Monoclonal Antibody
SKU:
CAB4335
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GABARAP (O95166).
Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.
Purification Method:
Affinity purification
Gene ID:
11337
Clone Number:
ARC1057
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using GABARAP Rabbit mAb (CAB4335) at 1:1000 dilution.293T、NIH/3T3 and C6 cells were treated by Chloroquine (50 μM) at 37℃ for 20 hours.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
