The GABARAP Polyclonal Antibody (CAB12568) is a valuable tool for researchers studying the GABARAP protein, a key player in autophagy and intracellular trafficking processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to GABARAP, researchers can easily detect and analyze this protein in various cell types, making it an ideal tool for studies in cell biology and neurodegenerative diseases.GABARAP is a crucial component of the autophagy pathway, a cellular process responsible for degrading and recycling damaged organelles and proteins.
Dysregulation of autophagy has been implicated in various diseases, including neurodegenerative disorders like Parkinson's and Alzheimer's disease. Understanding the role of GABARAP in autophagy is essential for developing targeted therapies to treat these conditions and improve overall cellular health.Overall, the GABARAP Polyclonal Antibody (CAB12568) is a reliable research tool for scientists studying autophagy and intracellular trafficking processes, with potential applications in drug discovery and therapeutic development for neurodegenerative diseases.
Product Name:
GABARAP Rabbit Polyclonal Antibody
SKU:
CAB12568
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GABARAP (NP_009209.1).
Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.
Purification Method:
Affinity purification
Gene ID:
11337
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GABARAP Rabbit pAb (CAB12568) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
