The Gab1 Polyclonal Antibody (CAB16856) is a valuable tool for researchers studying Gab1, a signaling adaptor protein involved in various cellular processes, including cell growth and differentiation. This rabbit-derived antibody is highly specific to Gab1 and is suitable for use in Western blot and immunofluorescence applications.Gab1 plays a crucial role in mediating signal transduction pathways activated by growth factors and cytokines, making it a key player in regulating cell proliferation and survival. Dysregulation of Gab1 signaling has been implicated in various diseases, including cancer and developmental disorders.
Therefore, understanding the function of Gab1 and its interacting partners is essential for developing targeted therapies.The Gab1 Polyclonal Antibody (CAB16856) offers high sensitivity and specificity, enabling precise detection and analysis of Gab1 expression in various cell types and tissues. By using this antibody, researchers can further elucidate the role of Gab1 in cell signaling pathways and its potential as a therapeutic target in disease intervention strategies.
Product Name:
GAB1 Rabbit Polyclonal Antibody
SKU:
CAB16856
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GAB1 (NP_997006.1).
The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2549
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using GAB1 Rabbit pAb (CAB16856) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
