The Gab1 Polyclonal Antibody (CAB6248) is a valuable tool for researchers studying Gab1, a protein involved in cellular signaling pathways and communication. This antibody, produced in rabbits, is highly specific for human samples and is perfect for use in Western blot applications. By binding to Gab1, this antibody allows for the detection and analysis of Gab1 expression in various cell types.Gab1 is known for its role in regulating cell growth, survival, and differentiation, making it a key player in processes like development and cancer progression.
Understanding the function of Gab1 is essential for uncovering its potential therapeutic implications in diseases like cancer and metabolic disorders. The Gab1 Polyclonal Antibody provides researchers with a reliable tool for investigating the role of Gab1 in cellular signaling pathways and identifying potential targets for therapeutic interventions.
Product Name:
GAB1 Rabbit Polyclonal Antibody
SKU:
CAB6248
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 594-694 of human GAB1 (NP_002030.2).
The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2549
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of SH-SY5Y cells, using GAB1 antibody (CAB6248) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 80s.
