GAA Rabbit Polyclonal Antibody (CAB7674)
- SKU:
- CAB7674
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GAA Rabbit Polyclonal Antibody |
SKU: | CAB7674 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human GAA (NP_000143.2). |
Sequence: | VVQQ YLDV VGYP FMPP YWGL GFHL CRWG YSST AITR QVVE NMTR AHFP LDVQ WNDL DYMD SRRD FTFN KDGF RDFP AMVQ ELHQ GGRR YMMI VDPA ISSS G |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | LYAG; GAA |
Positive Sample: | DU145,Mouse liver,Mouse ovary,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome, Lysosome membrane. |
Calculated MW: | 105kDa |
Observed MW: | 105kDa |
This gene encodes lysosomal alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2548 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |