The G Antibody (PAC04962) is a highly specific monoclonal antibody designed for research involving the G protein. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blot, ELISA, and immunohistochemistry.The G protein is a key regulator of intracellular signaling pathways, playing a critical role in numerous cellular processes such as cell growth, differentiation, and migration. Dysregulation of G protein signaling has been implicated in a wide range of diseases, including cancer, cardiovascular disorders, and neurological conditions. Therefore, understanding the function and regulation of the G protein is essential for developing targeted therapies for these diseases.
The G Antibody (PAC04962) provides researchers with a powerful tool for studying the G protein in different cell types and tissues. Its high specificity and sensitivity make it ideal for detecting and analyzing the expression levels of the G protein, facilitating in-depth investigations into its role in health and disease. By using this antibody, researchers can advance our understanding of the molecular mechanisms underlying various pathological conditions and accelerate the development of novel therapeutic strategies.
Antibody Name:
G Antibody (PACO34962)
Antibody SKU:
PACO34962
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human respiRatory syncytial virus A
Immunogen:
Recombinant Human respiratory syncytial virus A Major surface glycoprotein G protein (67-298AA)
Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities. Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcγ receptors.
Synonyms:
Major surface glycoprotein G (Attachment glycoprotein G) (Membrane-bound glycoprotein) (mG), G
UniProt Protein Function:
Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities.
