The G Antibody (PAC013462) is a high-quality polyclonal antibody developed for research purposes targeting the G protein-coupled receptor (GPCR). This antibody has been specifically designed to provide accurate and reliable results in Western blot applications, enabling the detection and analysis of the G protein in various cell types.The G protein is a crucial component in cellular signaling pathways and is involved in a wide range of physiological processes, making it a key focus in the fields of pharmacology and drug development. This antibody, raised in rabbits, is highly reactive with human samples, allowing for precise monitoring and investigation of G protein activity.
By targeting the G protein, researchers can gain insights into its role in cell signaling, neurotransmission, and other biological processes, facilitating advancements in drug discovery, neurobiology, and molecular biology. With its high specificity and sensitivity, the G Antibody (PAC013462) is an essential tool for studies aiming to unravel the mechanisms underlying GPCR signaling and its implications in various diseases and disorders.
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells ().
