The FZR1 Polyclonal Antibody (CAB5550) is an essential tool for researchers studying FZR1, a key regulator of the cell cycle and a critical component in cell division. This antibody, produced in rabbits, specifically targets the FZR1 protein and is highly reactive with human samples. Validated for use in Western blot applications, it allows for the detection and analysis of FZR1 in various cell types.FZR1, also known as Fizzy-related protein 1, plays a crucial role in controlling the progression of cells through the cell cycle by targeting specific proteins for degradation.
Its involvement in cell division makes it a promising target for research in cancer biology and developmental biology. By understanding the mechanisms by which FZR1 regulates the cell cycle, researchers can gain insights into the processes that drive tumor formation and growth.Overall, the FZR1 Polyclonal Antibody is a valuable tool for investigating the function and regulation of FZR1 in cellular processes, offering new possibilities for advancing our understanding of cell cycle control and its implications in disease development.
Product Name:
FZR1 Rabbit Polyclonal Antibody
SKU:
CAB5550
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 224-493 of human FZR1 (NP_057347.2).
Predicted to enable anaphase-promoting complex binding activity and ubiquitin ligase activator activity. Involved in anaphase-promoting complex-dependent catabolic process; mitotic G2 DNA damage checkpoint signaling; and positive regulation of protein metabolic process. Located in nuclear membrane and nucleoplasm. Colocalizes with anaphase-promoting complex.
Purification Method:
Affinity purification
Gene ID:
51343
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of 293T cells, using FZR1 antibody (CAB5550) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
