The Frizzled 9 Polyclonal Antibody (CAB8311) is a valuable tool for researchers studying the Frizzled 9 protein, a member of the Frizzled family of proteins involved in the Wnt signaling pathway. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the Frizzled 9 protein, this antibody allows for the detection and analysis of Frizzled 9 expression in various cell types, making it ideal for studies in developmental biology, cancer research, and regenerative medicine.Frizzled 9 is known to play a crucial role in the regulation of cell proliferation, differentiation, and migration, making it a key player in various biological processes.
Its dysregulation has been implicated in a range of diseases, including cancer, Alzheimer's disease, and developmental disorders. By understanding the function of Frizzled 9 and its role in disease pathology, researchers can gain important insights that may lead to the development of novel therapeutic interventions targeting the Wnt signaling pathway.In conclusion, the Frizzled 9 Polyclonal Antibody (CAB8311) is a valuable tool for researchers interested in studying the role of Frizzled 9 in various biological processes and disease states. Its high specificity and reliability make it an essential component of any research toolkit aimed at unraveling the mysteries of the Wnt signaling pathway.
Product Name:
FZD9 Rabbit Polyclonal Antibody
SKU:
CAB8311
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 469-591 of human FZD9 (NP_003499.1).
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.
Purification Method:
Affinity purification
Gene ID:
8326
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FZD9 antibody (CAB8311) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
