FZD8 Rabbit Polyclonal Antibody (CAB18393)
- SKU:
- CAB18393
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | FZD8 Rabbit Polyclonal Antibody |
SKU: | CAB18393 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-275 of human FZD8 (NP_114072.1). |
Sequence: | PDRM RCDR LPEQ GNPD TLCM DYNR TDLT TAAP SPPR RLPP PPPG EQPP SGSG HGRP PGAR PPHR GGGR GGGG GDAA APPA RGGG GGGK ARPP GGGA APCE PGCQ CRAP MVSV SSER HPLY NRVK TGQI ANCA LPCH NPFF SQDE RA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FZ-8; hFZ8; FZD8 |
Positive Sample: | 293T,A-549,HeLa,Mouse liver,Rat liver |
Cellular Localization: | Golgi apparatus, neuronal dense core vesicle, plasma membrane |
Calculated MW: | 73kDa |
Observed MW: | 73kDa |
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Purification Method: | Affinity purification |
Gene ID: | 8325 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |