FZD7 Rabbit Polyclonal Antibody (CAB4213)
- SKU:
- CAB4213
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | FZD7 Rabbit Polyclonal Antibody |
SKU: | CAB4213 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human FZD7 (NP_003498.1). |
Sequence: | MRDP GAAA PLSS LGLC ALVL ALLG ALSA GAGA QPYH GEKG ISVP DHGF CQPI SIPL CTDI AYNQ TILP NLLG HTNQ EDAG LEVH QFYP LVKV QCSP ELRF FLCS MYAP VCTV LDQA IPPC RSLC ERAR QGCE ALMN KFGF QWPE RLRC ENFP VHGA GEIC VGQN TSDG SGGP GGGP TAYP TAPY LPDL PFTA LPPG ASDG RGRP AFPF SCPR QLKV PPYL GYRF LGER DCGA PCEP GRAN GLMY FKEE ERRF ARLW VGVW |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FzE3; FZD7 |
Positive Sample: | SW480,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Membrane, Multi-pass membrane protein. |
Calculated MW: | 64kDa |
Observed MW: | 70-72kDa |
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Purification Method: | Affinity purification |
Gene ID: | 8324 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |