The FZD5 Polyclonal Antibody (CAB12775) is a vital tool for researchers studying the Frizzled-5 protein, a key component in the Wnt signaling pathway that plays a crucial role in development, cell differentiation, and disease progression. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human FZD5 samples, making it an ideal choice for Western blot applications.Frizzled-5 is known to be involved in various cellular processes, including cell proliferation, migration, and tissue polarity, making it a valuable target for research in developmental biology, cancer biology, and regenerative medicine. By targeting the FZD5 protein, researchers can gain insights into the mechanisms underlying disease development and potentially identify new therapeutic targets for diseases such as cancer and congenital disorders.
With its ability to detect and analyze FZD5 expression in different cell types, the FZD5 Polyclonal Antibody (CAB12775) serves as a valuable tool for researchers seeking to unravel the complexities of the Wnt signaling pathway and its implications in health and disease. Its utility in both basic research and drug discovery makes it an indispensable asset for laboratories focused on molecular biology and cell signaling studies.
Product Name:
FZD5 Rabbit Polyclonal Antibody
SKU:
CAB12775
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 130-240 of human FZD5 (NP_003459.2).
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
Purification Method:
Affinity purification
Gene ID:
7855
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat kidney, using FZD5 Rabbit pAb (CAB12775) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
