The FZD10 Polyclonal Antibody (CAB15399) is a valuable tool for researchers studying the Frizzled-10 (FZD10) protein, a member of the Frizzled family of proteins involved in Wnt signaling pathways. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications.FZD10 plays a key role in various cellular processes, including cell proliferation, differentiation, and migration. Dysregulation of the Wnt/FZD10 signaling pathway has been implicated in various diseases, such as cancer and developmental disorders. By binding to the FZD10 protein, this antibody allows for the accurate detection and analysis of FZD10 expression in different types of cells, providing valuable insights for researchers in the fields of developmental biology and oncology.
The FZD10 Polyclonal Antibody is a valuable tool for investigating the function and regulation of the FZD10 protein, and its role in cellular processes and disease development. By targeting FZD10, researchers can gain a better understanding of its biological functions and potential therapeutic applications in the treatment of diseases associated with aberrant Wnt signaling.
Product Name:
FZD10 Rabbit Polyclonal Antibody
SKU:
CAB15399
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 135-230 of human FZD10 (NP_009128.1).
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
Purification Method:
Affinity purification
Gene ID:
11211
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FZD10 Rabbit pAb (CAB15399) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
