The FYTTD1 Polyclonal Antibody (PACO39042) is a valuable tool for researchers studying FYTTD1, a protein involved in cellular processes such as autophagy and lysosomal degradation. This antibody, derived from rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the FYTTD1 protein, researchers can investigate its role in cell function and potentially uncover new therapeutic targets in diseases related to autophagy dysregulation.FYTTD1, also known as FYVE, WW domain-containing protein 1, is known to play a crucial role in mediating autophagy, a process vital for maintaining cellular homeostasis and eliminating damaged organelles and proteins.
Dysregulation of autophagy has been linked to various diseases, including neurodegenerative disorders and certain types of cancer. By studying FYTTD1 and its interactions within the autophagy pathway, researchers can gain insights into the underlying mechanisms of these diseases and potentially develop novel treatment strategies.Overall, the FYTTD1 Polyclonal Antibody is a valuable resource for researchers interested in exploring the role of FYTTD1 in cellular processes and its potential implications for disease pathogenesis. Its versatility in detecting FYTTD1 in different cell types makes it an essential tool for studies in cell biology, molecular biology, and disease mechanisms.
Antibody Name:
FYTTD1 Antibody (PACO39042)
Antibody SKU:
PACO39042
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Recombinant Human UAP56-interacting factor protein (1-318AA)
Western blot. All lanes: FYTTD1 antibody at 4µg/ml. Lane 1: A375 whole cell lysate. Lane 2: Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 36, 34, 29, 15 kDa. Observed band size: 36 kDa.
Background:
Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4.
Synonyms:
UAP56-interacting factor (Forty-two-three domain-containing protein 1) (Protein 40-2-3), FYTTD1, UIF
UniProt Protein Function:
FYTTD1: Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4. Belongs to the UIF family. 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3q29Cellular Component: nuclear speck; nucleoplasmMolecular Function: mRNA binding; protein bindingBiological Process: mRNA export from nucleus
