The FXYD6 Polyclonal Antibody (CAB14339) is a valuable tool for researchers studying the FXYD6 protein, which is known for its involvement in ion transport and regulation of Na,K-ATPase activity. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the FXYD6 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in physiology, cell biology, and drug discovery.
FXYD6, also referred to as phospholemman-like protein, plays a crucial role in maintaining ion homeostasis and cell membrane potential by modulating the activity of Na,K-ATPase. Its importance in ion transport regulation makes it a promising target for research related to cardiovascular diseases, neurological disorders, and kidney function. Investigating the function of FXYD6 can provide insights into potential therapeutic strategies for conditions influenced by ion dysregulation.
Product Name:
FXYD6 Rabbit Polyclonal Antibody
SKU:
CAB14339
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human FXYD6 (NP_071286.1).
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes phosphohippolin, which likely affects the activity of Na,K-ATPase. Multiple alternatively spliced transcript variants encoding the same protein have been described. Related pseudogenes have been identified on chromosomes 10 and X. Read-through transcripts have been observed between this locus and the downstream sodium/potassium-transporting ATPase subunit gamma (FXYD2, GeneID 486) locus.
Purification Method:
Affinity purification
Gene ID:
53826
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FXYD6 Rabbit pAb (CAB14339) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
