The FXR2 Polyclonal Antibody (CAB14092) is a valuable tool for researchers investigating FXR2, a member of the fragile X-related family of RNA-binding proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the FXR2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and neurodevelopmental disorders.FXR2 plays a crucial role in RNA metabolism and translation regulation, making it a key player in cellular processes such as synaptic plasticity and neuronal development.
Dysregulation of FXR2 has been implicated in disorders like fragile X syndrome, autism spectrum disorders, and intellectual disabilities, underscoring the importance of further research into its function and mechanisms of action. The FXR2 Polyclonal Antibody is a valuable tool for scientists seeking to deepen their understanding of FXR2 and its implications in neurological disorders and RNA biology.
Product Name:
FXR2 Rabbit Polyclonal Antibody
SKU:
CAB14092
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 550-650 of human FXR2 (NP_004851.2).
The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitive disability syndrome.
Purification Method:
Affinity purification
Gene ID:
9513
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FXR2 antibody (CAB14092) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
