The FXR1 Polyclonal Antibody (CAB5942) is a valuable tool for researchers studying the FXR1 protein, a member of the Fragile X-related family of RNA binding proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the FXR1 protein, this antibody enables the detection and analysis of FXR1 in various cell types, making it an essential component for studies in molecular biology, RNA regulation, and neurodevelopmental disorders.FXR1 is known to play a crucial role in RNA metabolism, translational control, and synaptic plasticity, making it a key player in neurological function and development.
Dysregulation of FXR1 has been linked to disorders such as Fragile X syndrome, autism spectrum disorders, and other neurodevelopmental conditions. Understanding the function and regulation of FXR1 is vital in uncovering the mechanisms underlying these disorders and developing targeted therapies.Overall, the FXR1 Polyclonal Antibody (CAB5942) is a reliable tool for researchers investigating the function and regulation of the FXR1 protein in various physiological and pathological conditions. Its high specificity and sensitivity make it an indispensable asset for advancing our understanding of RNA binding proteins and their roles in health and disease.
Product Name:
FXR1 Rabbit Polyclonal Antibody
SKU:
CAB5942
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human FXR1 (NP_005078.2).
The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8087
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FXR1 antibody (CAB5942) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
