FUT3 Rabbit Polyclonal Antibody (CAB15058)
- SKU:
- CAB15058
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | FUT3 Rabbit Polyclonal Antibody |
SKU: | CAB15058 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FUT3 (NP_000140.1). |
Sequence: | MDPL GAAK PQWP WRRC LAAL LFQL LVAV CFFS YLRV SRDD ATGS PRAP SGSS RQDT TPTR PTLL ILLW TWPF HIPV ALSR CSEM VPGT ADCH ITAD RKVY |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LE; Les; FT3B; CD174; FucT-III; FUT3 |
Positive Sample: | A-549,HT-29,293T,LO2 |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein. |
Calculated MW: | 42kDa |
Observed MW: | 50kDa |
The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Differences in the expression of this gene are associated with host susceptibility to viral infection.
Purification Method: | Affinity purification |
Gene ID: | 2525 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |