Based on the information provided in the URL for the FUT2 Polyclonal Antibody (CAB5721), the antibody is specifically designed for research involving FUT2, a gene associated with the production of enzymes that contribute to the synthesis of blood group antigens. The antibody is raised in rabbits and has high reactivity with human samples, making it suitable for various research applications.FUT2 plays a crucial role in the determination of blood group phenotypes and is associated with susceptibility to various infectious diseases. The antibody binds to the FUT2 protein, allowing for the detection and analysis of its expression in different cell types.
This makes it a valuable tool for studies in the fields of glycobiology, immunology, and infectious diseases.Understanding the function of FUT2 is important for investigating its role in immune response modulation, host-pathogen interactions, and disease susceptibility. Research using the FUT2 Polyclonal Antibody can provide insights into the molecular mechanisms underlying these processes, with potential implications for the development of novel therapeutic strategies in personalized medicine.
Product Name:
FUT2 Rabbit Polyclonal Antibody
SKU:
CAB5721
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-150 of human FUT2 (NP_001091107.1).
Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein.
Calculated MW:
39kDa
Observed MW:
35kDa
This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. The encoded protein is important for the final step in the soluble ABO blood group antigen synthesis pathway. It is also involved in cell-cell interaction, cell surface expression, and cell proliferation. Mutations in this gene are a cause of the H-Bombay blood group where red blood cells lack the H antigen.
Purification Method:
Affinity purification
Gene ID:
2524
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HT-29 cells, using FUT2 Rabbit pAb (CAB5721) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
