The FUT1 Polyclonal Antibody (CAB15585) is a powerful tool for research involving FUT1, an enzyme involved in the biosynthesis of H type 1 and Lewis antigens on red blood cells and mucosal epithelia. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to the FUT1 protein, this antibody enables precise detection and analysis in various cell types, making it an ideal choice for studies in glycobiology and transfusion medicine.
FUT1, also known as alpha (1,2) fucosyltransferase, plays a crucial role in the synthesis of certain blood group antigens, influencing blood compatibility and immune reactions. Understanding the function of FUT1 is essential for research into blood transfusion compatibility, organ transplantation, and genetic disorders related to blood group antigens. The FUT1 Polyclonal Antibody offers researchers a reliable tool for investigating the complex processes involving FUT1 and its impact on human health.
Product Name:
FUT1 Rabbit Polyclonal Antibody
SKU:
CAB15585
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 130-310 of human FUT1 (NP_000139.1).
Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein.
Calculated MW:
41kDa
Observed MW:
55kDa
This gene encodes a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the synthesis of soluble A and B antigens. This is one of two genes encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group.
Purification Method:
Affinity purification
Gene ID:
2523
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat brain, using FUT1 Rabbit pAb (CAB15585) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
