FTO Rabbit Polyclonal Antibody (CAB1438)
- SKU:
- CAB1438
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | FTO Rabbit Polyclonal Antibody |
SKU: | CAB1438 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 327-504 of human FTO (NP_001073901.1). |
Sequence: | STGT LDYI LQRC QLAL QNVC DDVD NDDV SLKS FEPA VLKQ GEEI HNEV EFEW LRQF WFQG NRYR KCTD WWCQ PMAQ LEAL WKKM EGVT NAVL HEVK REGL PVEQ RNEI LTAI LASL TARQ NLRR EWHA RCQS RIAR TLPA DQKP ECRP YWEK DDAS MPLP FDLT DIVS ELRG QLLE AK |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | GDFD; ALKBH9; BMIQ14; FTO |
Positive Sample: | HeLa,293T,SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Nucleus speckle. |
Calculated MW: | 58kDa |
Observed MW: | 60kDa |
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Purification Method: | Affinity purification |
Gene ID: | 79068 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |