The FTCD Monoclonal Antibody (CAB22655) is a valuable tool for researchers studying FTCD, a crucial enzyme involved in amino acid metabolism and the production of one-carbon units. This monoclonal antibody, generated in mice, exhibits high specificity and sensitivity for FTCD in human samples, making it a reliable choice for various immunoassays, including Western blot and immunohistochemistry.FTCD, also known as formimidoyltransferase cyclodeaminase, plays a key role in the breakdown of histidine and the synthesis of formiminotransferase cyclodeaminase (FTCD). Dysregulation of FTCD has been linked to various diseases, including neurodegenerative disorders and cancer.
Studying the expression and activity of FTCD using this monoclonal antibody can provide valuable insights into the role of this enzyme in health and disease.Researchers in the fields of biochemistry, molecular biology, and biomedicine will find the FTCD Monoclonal Antibody (CAB22655) to be a reliable reagent for their studies on FTCD function and regulation. Its high specificity and versatility in applications make it a valuable asset for projects aiming to unravel the complexities of amino acid metabolism and its implications for human health.
The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10841
Clone Number:
ARC58234
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using FTCD antibody (CAB22655) at 1:8000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
