The FSP1/S100A4 Polyclonal Antibody is a valuable tool for researchers studying FSP1 and S100A4 proteins, which are implicated in cancer progression and metastasis. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the FSP1 and S100A4 proteins, this antibody allows for accurate detection and analysis in a wide range of cell types, making it ideal for studies in cancer biology and tumor metastasis.FSP1 and S100A4 play key roles in promoting epithelial to mesenchymal transition (EMT) and enhancing tumor cell migration and invasion.
Understanding the function and regulation of these proteins is crucial for developing targeted therapies to inhibit cancer spread and metastasis. The FSP1/S100A4 Polyclonal Antibody provides researchers with a reliable tool to investigate the expression and activity of these proteins in cancer cells, offering insights that may lead to novel therapeutic strategies in the fight against cancer.
Product Name:
FSP1/S100A4 Polyclonal Antibody
SKU:
CAB21808
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human FSP1/S100A4 (NP_002952.1).
extracellular exosome, extracellular region, extracellular space, neuron projection, nucleus, perinuclear region of cytoplasm
Calculated MW:
12kDa
Observed MW:
Refer to figures
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
6275
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FSP1/S100A4 Rabbit pAb (CAB21808) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
