The FSCN2 Polyclonal Antibody (CAB16508) is a valuable tool for researchers studying FSCN2, a key protein involved in actin bundling and cytoskeletal organization. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in techniques such as Western blotting. By specifically binding to the FSCN2 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for research in cell biology, cancer, and developmental biology.FSCN2 plays a crucial role in maintaining cell morphology and function by promoting the formation of actin bundles, which are essential for cellular movement and shape.
Dysregulation of FSCN2 expression has been linked to various diseases, including cancer metastasis and neurodevelopmental disorders, making it a promising target for therapeutic interventions. Understanding the function and regulation of FSCN2 is vital for advancing our knowledge of these diseases and potentially developing new treatment strategies.
Product Name:
FSCN2 Rabbit Polyclonal Antibody
SKU:
CAB16508
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human FSCN2 (NP_036550.1).
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
25794
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FSCN2 Rabbit pAb (CAB16508) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
