FSCN1 Monoclonal Antibody [PAT13D2AT] (CPAB0637)
- SKU:
- CPAB0637
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT13D2AT
- Applications:
- WB
- ELISA
- FC
Description
FSCN1 Monoclonal Antibody [PAT13D2AT] (CPAB0637)
The FSCN1 Polyclonal Antibody (CPAB0637) is a valuable tool for researchers studying FSCN1, a protein involved in cell migration and invasion processes in cancer. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot and immunohistochemistry applications. By targeting the FSCN1 protein, this antibody allows for the detection and analysis of FSCN1 expression in a variety of cell types, making it ideal for studies in cancer biology and metastasis research.
FSCN1 is a key player in promoting cell motility and invasiveness, making it a promising target for therapeutic interventions in cancer treatment. Its role in driving tumor progression and metastasis highlights the importance of investigating its expression and function in different cancer types. By understanding the mechanisms by which FSCN1 contributes to cancer metastasis, researchers can identify potential targets for drug development and personalized cancer therapy strategies.
Product Name: | FSCN1 Antibody |
Product Sku: | CPAB0637 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human FSCN1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FSCN1 protein 1-493 amino acids purified from Ecoli. |
Clone: | PAT13D2AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA, Flow Cytometry |
Purification Method: | FSCN1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2a |
Background: | FSCN1 is an actin-bundling protein that is responsible for rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. FSCN1 takes part in the gathering of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. FSCN1 is absent from most normal epithelia though is upregulated in multiple forms of human carcinoma, where its expression associates clinically with a poor prognosis. FSCN1 expression is abundantly found in neurons, glial cells, and endothelial cells. |
Synonyms: | Strongylocentrotus Purpuratus, actin-bundling protein, FAN1, HSN, SNL. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |