The FRZB Polyclonal Antibody (CAB6592) is a valuable tool for researchers studying FRZB, a secreted glycoprotein involved in the Wnt signaling pathway. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.FRZB plays a vital role in regulating cell proliferation, differentiation, and migration, making it a key player in developmental processes and disease progression. By targeting FRZB with this polyclonal antibody, researchers can effectively detect and analyze FRZB expression in different cell types, providing crucial insights into its functions in various biological processes.
Studies have shown that dysregulation of FRZB expression is associated with various diseases, including cancer, osteoarthritis, and cardiovascular diseases. Therefore, understanding the role of FRZB in these conditions could lead to potential therapeutic interventions targeting the Wnt signaling pathway.Overall, the FRZB Polyclonal Antibody (CAB6592) offers researchers a reliable tool for investigating the function of FRZB in health and disease, opening up new avenues for research in the fields of developmental biology, oncology, and regenerative medicine.
Product Name:
FRZB Rabbit Polyclonal Antibody
SKU:
CAB6592
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 166-325 of human FRZB (NP_001454.2).
The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
Purification Method:
Affinity purification
Gene ID:
2487
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat spleen, using FRZB Rabbit pAb (CAB6592) at 1:6000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
