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FPS/FDPS Monoclonal Antibody

SKU:
CAB23475
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
Frequently bought together:

Description

FPS/FDPS Monoclonal Antibody (CAB23475)

The FPS/FDPS Monoclonal Antibody is a cutting-edge research tool designed for scientists studying the FPS/FDPS protein, which plays a key role in the mevalonate pathway and is essential for cholesterol biosynthesis. This monoclonal antibody, produced using innovative technologies, specifically targets the FPS/FDPS protein and has been validated for use in various applications, including Western blot and immunohistochemistry.The FPS/FDPS protein is a critical enzyme involved in the production of isoprenoids, which are essential for cell growth and survival. Dysregulation of the mevalonate pathway, including abnormalities in FPS/FDPS function, has been implicated in various diseases, such as cancer and metabolic disorders.

Studying the expression and activity of FPS/FDPS using this monoclonal antibody can provide valuable insights into the underlying mechanisms of these diseases and may lead to the development of novel therapeutic strategies targeting the mevalonate pathway. Overall, the FPS/FDPS Monoclonal Antibody is a versatile tool that can enhance research efforts in molecular biology, biochemistry, and drug discovery, ultimately advancing our understanding of FPS/FDPS function and its implications in human health and disease.

Product Name:FPS/FDPS Monoclonal Antibody
Product Code:CAB23475
Reactivity:Human, Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC56378
Reactivity:Human, Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:2000-1:20000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:HepG2, BxPC-3, Mouse liver, Mouse brain, Rat liver, Rat testis
Cellular Location:Cytoplasm

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen:Recombinant protein of human FPS/FDPS.
Sequence:Email for sequence
Synonyms:FPS, FPPS, POROK9
Calculated MW:48kDa
Observed MW:41kDa

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