Anti-FPR3 Antibody (PACO53018)

Antibody Name:	FPR3 Antibody (PACO53018)
Antibody SKU:	PACO53018
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IHC, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200
Species Reactivity:	Human
Immunogen:	Recombinant Human N-formyl peptide receptor 3 protein (307-353AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO53018 at dilution of 1:100.
	Immunofluorescent analysis of A549 cells using PACO53018 at dilution of 1:100 and Cy3-congugated Goat Anti-Rabbit IgG.
	Immunohistochemistry of paraffin-embedded human colon cancer using PACO53018 at dilution of 1:100.

Background:	Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Synonyms:	N-formyl peptide receptor 3 (FMLP-related receptor II) (FMLP-R-II) (Formyl peptide receptor-like 2), FPR3, FPRH1 FPRL2

UniProt Protein Function:	FPR3: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; GPCR, family 1; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 19q13.3-q13.4Cellular Component: plasma membraneBiological Process: cell motility; signal transduction
UniProt Protein Details:
NCBI Summary:
UniProt Code:	P25089
NCBI GenInfo Identifier:	38258904
NCBI Gene ID:	2359
NCBI Accession:	P25089.2
UniProt Secondary Accession:	P25089
UniProt Related Accession:	P25089
Molecular Weight:	39,965 Da
NCBI Full Name:	N-formyl peptide receptor 3
NCBI Synonym Full Names:	formyl peptide receptor 3
NCBI Official Symbol:	FPR3
NCBI Official Synonym Symbols:	FMLPY; FPRH1; FPRH2; FPRL2; RMLP-R-I; FMLP-R-II; FML2_HUMAN
NCBI Protein Information:	N-formyl peptide receptor 3
UniProt Protein Name:	N-formyl peptide receptor 3
UniProt Synonym Protein Names:	FMLP-related receptor II; FMLP-R-II; Formyl peptide receptor-like 2
Protein Family:	FK506-binding protein
UniProt Gene Name:	FPR3
UniProt Entry Name:	FPR3_HUMAN

Antibodies

Secondary Antibody