The FPR3 Polyclonal Antibody (PACO03724) is a valuable tool for researchers studying formyl peptide receptor 3 (FPR3), a G-protein coupled receptor involved in inflammation and immune response. This antibody, produced in rabbits, is highly specific to FPR3 and has been validated for use in various applications, including Western blot and immunohistochemistry.FPR3, a member of the formyl peptide receptor family, plays a key role in the recognition and response to bacterial infections and inflammation. By targeting FPR3, researchers can gain insights into the mechanisms underlying these processes and potentially identify new therapeutic targets for conditions such as sepsis, inflammatory diseases, and cancer.
This FPR3 Polyclonal Antibody is an essential tool for investigating the function and expression of FPR3 in different cell types and tissues, providing valuable information for studies in immunology, infectious diseases, and inflammatory conditions. Its high specificity and sensitivity make it a reliable choice for researchers looking to advance our understanding of FPR3 and its role in the immune system.
Antibody Name:
FPR3 Antibody
Antibody SKU:
PACO03724
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human FPRL2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
FPR3: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; GPCR, family 1; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 19q13.3-q13.4Cellular Component: plasma membraneBiological Process: cell motility; signal transduction
