The FOXR1 Polyclonal Antibody (PAC00822) is a powerful tool for researchers studying the FOXR1 protein, a transcription factor involved in various cellular processes, including development, differentiation, and cancer progression. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in Western blot applications. It recognizes the FOXR1 protein, allowing for accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in developmental biology and oncology research.FOXR1 plays a crucial role in controlling gene expression and signaling pathways involved in cell growth and differentiation.
Its dysregulation has been implicated in various cancers, making it a promising target for therapeutic interventions. By studying the function of FOXR1, researchers can gain valuable insights into cancer biology and potentially identify new strategies for cancer treatment and prevention.Overall, the FOXR1 Polyclonal Antibody is a valuable research tool for investigating the role of FOXR1 in cellular processes and disease development. Its high specificity and sensitivity make it a reliable option for researchers looking to advance our understanding of the molecular mechanisms underlying cancer and other diseases.
Antibody Name:
FOXR1 Antibody
Antibody SKU:
PACO00822
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the C-terminal region of human FoxR1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
FOXR1; FOXN5; DLNB13; Forkhead box protein R1; Forkhead box protein N5
UniProt Protein Function:
FOXR1: 2 isoforms of the human protein are produced by alternative splicingProtein type: Transcription factor; DNA-bindingChromosomal Location of Human Ortholog: 11q23.3Cellular Component: nucleusMolecular Function: sequence-specific DNA bindingBiological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the forkhead box (FOX) family of transcription factors. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 aa. Many FOX transcription factors play roles in determining cell fates during early development. This forkhead box protein lacks the C-terminal basic region found in many other FOX family members. It is located within the 11q23.3 region which is commonly deleted in neuroblastomas. [provided by RefSeq, Jul 2008]
