The Foxp3 Polyclonal Antibody (CAB5706) is a valuable tool for researchers studying Foxp3, a key regulatory T cell transcription factor involved in immune regulation and tolerance. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it suitable for various research applications, including Western blot analysis.Foxp3, also known as forkhead box protein P3, plays a crucial role in maintaining immune tolerance by regulating the development and function of regulatory T cells (Tregs). Dysregulation of Foxp3 expression has been linked to autoimmune diseases, allergies, and cancer.
By targeting Foxp3, researchers can gain insights into the mechanisms underlying immune tolerance and explore potential therapeutic interventions for immune-related disorders.This Foxp3 Polyclonal Antibody is an essential tool for immunologists and cancer researchers seeking to investigate the role of regulatory T cells in immune homeostasis and disease progression. Its specificity and sensitivity make it a reliable choice for analyzing Foxp3 expression levels in various cell types, paving the way for advancements in immunotherapy and precision medicine.
Product Name:
FOXP3 Rabbit Polyclonal Antibody
SKU:
CAB5706
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 206-300 of human FOXP3 (NP_054728.2).
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
50943
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse thymus , using FOXP3 Rabbit pAb (CAB5706) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
