The FOXO3A Rabbit Monoclonal Antibody (CAB9270) is a valuable tool for researchers studying FOXO3A, a transcription factor that plays a key role in regulating cell cycle progression, apoptosis, and oxidative stress response. This antibody, raised in rabbits, has high specificity and sensitivity to human samples, making it ideal for use in Western blot applications.FOXO3A is a crucial mediator of cellular responses to stress and is involved in the regulation of longevity and age-related diseases. Dysregulation of FOXO3A has been linked to various health conditions including cancer, neurodegenerative diseases, and cardiovascular disorders.
By targeting FOXO3A with this monoclonal antibody, researchers can gain insight into its function and potential therapeutic implications in these disease contexts.With its ability to specifically detect FOXO3A protein in various cell types, this monoclonal antibody is a valuable tool for investigating the molecular mechanisms underlying aging, longevity, and disease pathogenesis. Its high reactivity and reliability make it an essential component for studies in cell biology, molecular biology, and biomedicine.
Product Name:
FOXO3A Rabbit Monoclonal Antibody
SKU:
CAB9270
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 574-673 of human FOXO3A (NP_001446.1).
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
Purification Method:
Affinity purification
Gene ID:
2309
Clone Number:
ARC1505
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FOXO3A Rabbit mAb (CAB9270) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
