The FOXO1/FOXO3a/FOXO4 Rabbit Polyclonal Antibody (CAB17978) is a valuable tool for researchers studying the FOXO family of transcription factors. These proteins are critical regulators of various cellular processes, including cell cycle progression, apoptosis, and glucose metabolism. The antibody, generated in rabbits, shows high specificity for human samples and has been validated for use in Western blot applications.By targeting all three FOXO isoforms (FOXO1, FOXO3a, and FOXO4), this antibody allows for comprehensive analysis of FOXO protein expression and activity in different cell types and experimental conditions.
Understanding the role of FOXO transcription factors is essential for unraveling their involvement in aging, metabolism, and cancer development.The FOXO1/FOXO3a/FOXO4 Rabbit Polyclonal Antibody is a versatile tool for researchers interested in studying the intricate signaling pathways regulated by FOXO proteins. Its high reactivity and specificity make it a reliable choice for investigations into the roles of FOXO transcription factors in health and disease.
Product Name:
FoxO1/FoxO3a/FoxO4 Rabbit Polyclonal Antibody
SKU:
CAB17978
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide of human FOXO1/FOXO3A/FOXO4 (NP_002006.2).
The Forkhead family of transcription factors mediates many aspects of physiology, including stress response, metabolism, commitment to apoptosis, and development. The Forkhead box subfamily O (FoxO) proteins have garnered particular interest due to their involvement in the modulation of cancer, metabolism and cardiovascular biology.In mammals, four subfamily members have been identified: FOXO1 (previously also known as FKHR), FOXO3 (also known as FKHRL1), FOXO4 (also known as AFX),and FOXO6.
Purification Method:
Affinity purification
Gene ID:
2308/2309/4303
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FOXO1/FOXO3A/FOXO4 Rabbit pAb (CAB17978) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
