The FOXl2 Polyclonal Antibody (CAB16244) is a specialized tool for research involving the FOXl2 protein, a transcription factor essential for ovarian development and function. This antibody, produced in rabbits, exhibits high reactivity with human and mouse samples and has been validated for use in various experimental techniques, including Western blot and immunohistochemistry.FOXl2 is a key regulator of granulosa cell differentiation and folliculogenesis, making it a vital player in reproductive biology and ovarian health. Dysregulation of FOXl2 has been implicated in ovarian disorders and reproductive cancers, highlighting its significance in clinical research and therapeutic development.
By enabling the detection and analysis of FOXl2 protein expression in biological samples, this polyclonal antibody is an indispensable tool for investigating the molecular mechanisms underlying ovarian development, ovarian cancer, and other reproductive pathologies. Researchers can utilize this antibody to gain insights into the function of FOXl2 and its involvement in various physiological and pathological processes, paving the way for new discoveries in the field of reproductive biology and personalized medicine.
Product Name:
FOXL2 Rabbit Polyclonal Antibody
SKU:
CAB16244
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-376 of human FOXL2 (NP_075555.1).
This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Expansion of a polyalanine repeat region and other mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3.
Purification Method:
Affinity purification
Gene ID:
668
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using (CAB16244) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
