The FOXI1 Polyclonal Antibody (CAB16852) is a valuable tool for researchers studying FOXI1, a transcription factor involved in the development and function of the inner ear and other tissues. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the FOXI1 protein, this antibody allows for accurate detection and analysis in various cell types, making it ideal for studies in developmental biology and sensory system research.FOXI1 plays a crucial role in the regulation of genes involved in the formation of sensory hair cells in the inner ear, as well as in the development of other organs like the kidney and thyroid.
Its importance in these processes makes FOXI1 a key target for investigation in disorders related to hearing loss, kidney development, and thyroid function. By gaining insight into the functions of FOXI1, researchers can better understand the molecular mechanisms underlying these conditions and potentially develop new therapeutic strategies for treating them.
Product Name:
FOXI1 Rabbit Polyclonal Antibody
SKU:
CAB16852
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FOXI1 (NP_036320.2).
This gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene may play an important role in the development of the cochlea and vestibulum, as well as in embryogenesis. The encoded protein has been found to be required for the transcription of four subunits of a proton pump found in the inner ear, the kidney, and the epididymis. Mutations in this gene have been associated with deafness, autosomal recessive 4.
Purification Method:
Affinity purification
Gene ID:
2299
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using FOXI1 Rabbit pAb (CAB16852) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
