The FOXG1 Polyclonal Antibody (CAB16851) is a valuable tool for researchers studying the FOXG1 protein, a key transcription factor involved in brain development and neural differentiation. This antibody, raised in rabbits, is highly specific to human FOXG1 samples and is validated for use in various applications, including Western blot and immunohistochemistry.FOXG1 is essential for proper brain development, regulating the expression of genes necessary for neuronal growth and function. Mutations in the FOXG1 gene are associated with neurological disorders, making it a target of interest for researchers studying neurodevelopmental diseases such as Rett Syndrome and autism spectrum disorders.
By using the FOXG1 Polyclonal Antibody, researchers can detect and analyze FOXG1 protein expression in different cell types and tissues, providing valuable insights into its role in brain development and disease pathology. Understanding the functions of FOXG1 is paramount for developing targeted therapies for neurological disorders and advancing our knowledge of neurodevelopmental processes.
Product Name:
FOXG1 Rabbit Polyclonal Antibody
SKU:
CAB16851
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-489 of human FOXG1 (NP_005240.3).
This locus encodes a member of the fork-head transcription factor family. The encoded protein, which functions as a transcriptional repressor, is highly expressed in neural tissues during brain development. Mutations at this locus have been associated with Rett syndrome and a diverse spectrum of neurodevelopmental disorders defined as part of the FOXG1 syndrome. This gene is disregulated in many types of cancer and is the target of multiple microRNAs that regulate the proliferation of tumor cells.
Purification Method:
Affinity purification
Gene ID:
2290
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FOXG1 antibody (CAB16851) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
