The FOXF2 Polyclonal Antibody (PAC05090) is a valuable tool for researchers studying the FOXF2 protein, a transcription factor involved in various cellular processes, including development, differentiation, and cancer progression. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot and immunohistochemistry applications.FOXF2 is known to regulate gene expression and cell behavior, making it a key player in developmental processes and disease progression. Its involvement in pathways related to cell migration, invasion, and metastasis suggests its potential as a therapeutic target in cancer research.
The FOXF2 Polyclonal Antibody enables researchers to detect and analyze FOXF2 expression in different cell types, allowing for a better understanding of its role in both normal and pathological conditions. By studying the activity and regulation of FOXF2, researchers can gain insights into its impact on cellular functions and its potential as a biomarker or therapeutic target in cancer and other diseases. The FOXF2 Polyclonal Antibody provides a reliable tool for investigating the functions and mechanisms of this important transcription factor in various biological contexts.
Antibody Name:
FOXF2 Antibody (PACO50590)
Antibody SKU:
PACO50590
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Forkhead box protein F2 protein (226-364AA)
Probable transcription activator for a number of lung-specific genes.
Synonyms:
Forkhead box protein F2 (Forkhead-related activator 2) (FREAC-2) (Forkhead-related protein FKHL6) (Forkhead-related transcription factor 2), FOXF2, FKHL6 FREAC2
UniProt Protein Function:
FOXF2: Probable transcription activator for a number of lung- specific genes.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 6p25.3Cellular Component: transcription factor complex; nucleusMolecular Function: DNA binding; sequence-specific DNA binding; transcription factor binding; transcription factor activityBiological Process: genitalia development; extracellular matrix organization and biogenesis; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; epithelial to mesenchymal transition; positive regulation of transcription from RNA polymerase II promoter; embryonic camera-type eye morphogenesis; palate development; negative regulation of transcription, DNA-dependent; embryonic gut development; establishment of polarity of embryonic epithelium
UniProt Protein Details:
NCBI Summary:
FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. [provided by RefSeq, Jul 2008]
