The FOXD4/FOXD4L4/FOXD4L5/FOXD4L2/FOXD4L3/FOXD4L6 Polyclonal Antibody (PACO05083) is a versatile tool for researchers studying the FOXD4 family of transcription factors. This antibody, raised in rabbits, is highly specific for FOXD4, FOXD4L4, FOXD4L5, FOXD4L2, FOXD4L3, and FOXD4L6 proteins, enabling detection and analysis in a variety of cell types and tissues.The FOXD4 family of transcription factors plays a crucial role in the regulation of gene expression, specifically in the development and differentiation of various cell types.
Dysregulation of these proteins has been implicated in a range of diseases, including cancer, developmental disorders, and autoimmune conditions. By utilizing the FOXD4/FOXD4L4/FOXD4L5/FOXD4L2/FOXD4L3/FOXD4L6 Polyclonal Antibody, researchers can further investigate the function and significance of these transcription factors in both normal physiology and disease pathogenesis.
Synthesized peptide derived from the Internal region of human FoxD4/D4L.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
FOXD4; FKHL9; FOXD4A; FREAC5; Forkhead box protein D4; Forkhead-related protein FKHL9; Forkhead-related transcription factor 5; FREAC-5; Myeloid factor-α; FOXD4L4; FOXD4B; Forkhead box protein D4-like 4; FOXD4-like 4; Forkhead box prote
UniProt Protein Function:
FOXD4: Protein type: Transcription factor; DNA-bindingChromosomal Location of Human Ortholog: 9p24.3Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; transcription factor activity; DNA bending activityBiological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. Mutations in this gene are associated with a complex phenotype consisting of dilated cardiomyopathy, obsessive-compulsive disorders, and suicidality. [provided by RefSeq, Mar 2012]