The FOXD4 Antibody (PAC022334) is a polyclonal antibody specifically designed for research related to FOXD4, a transcription factor involved in the regulation of gene expression. This antibody, produced in rabbits, is highly sensitive and reactive with human samples, making it suitable for use in various applications such as Western blotting and immunohistochemistry.FOXD4 is known to play a role in the development of various tissues and organs, including the brain and heart. It is also implicated in the regulation of stem cell pluripotency and differentiation processes. As such, studying the expression and function of FOXD4 can provide valuable insights into developmental biology, tissue regeneration, and disease mechanisms.
Researchers interested in exploring the role of FOXD4 in various biological processes, including embryonic development, cell differentiation, and disease progression, will find the FOXD4 Antibody (PAC022334) to be a valuable tool for their studies. Its high specificity and sensitivity ensure reliable and accurate detection of FOXD4 protein levels, allowing for detailed analysis and characterization of FOXD4 function in different cellular contexts.
Antibody Name:
FOXD4 Antibody (PACO22334)
Antibody SKU:
PACO22334
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from Internal of human FOXD4.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from NIH-3T3 cells, using FOXD4 antibody.
Background:
This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. Mutations in this gene are associated with a complex phenotype consisting of dilated cardiomyopathy, obsessive-compulsive disorders, and suicidality.
Synonyms:
FKHL9; forkhead box D4; forkhead box protein D4; forkhead; Drosophila
UniProt Protein Function:
FOXD4: Protein type: Transcription factor; DNA-bindingChromosomal Location of Human Ortholog: 9p24.3Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; transcription factor activity; DNA bending activityBiological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. Mutations in this gene are associated with a complex phenotype consisting of dilated cardiomyopathy, obsessive-compulsive disorders, and suicidality. [provided by RefSeq, Mar 2012]
