The FOXD4 Polyclonal Antibody (PACO02741) is a valuable tool for researchers studying the FOXD4 protein, a transcription factor involved in developmental processes and cancer progression. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting. By targeting the FOXD4 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in developmental biology and oncology.FOXD4 is a critical regulator of gene expression, playing a key role in embryonic development and cell differentiation.
Its involvement in cancer progression makes it an attractive target for research aimed at understanding the mechanisms underlying tumorigenesis. By investigating the function of FOXD4, researchers can gain insights into the processes driving developmental abnormalities and cancer growth, potentially leading to the development of targeted therapies for these diseases. Overall, the FOXD4 Polyclonal Antibody (PACO02741) is a valuable resource for researchers looking to explore the role of FOXD4 in various biological processes, offering a reliable tool for the detection and analysis of this important transcription factor.
Antibody Name:
FOXD4 Antibody
Antibody SKU:
PACO02741
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the Internal region of human FoxD4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
FOXD4; FKHL9; FOXD4A; FREAC5; Forkhead box protein D4; Forkhead-related protein FKHL9; Forkhead-related transcription factor 5; FREAC-5; Myeloid factor-alpha
UniProt Protein Function:
FOXD4: Protein type: Transcription factor; DNA-bindingChromosomal Location of Human Ortholog: 9p24.3Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; transcription factor activity; DNA bending activityBiological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. Mutations in this gene are associated with a complex phenotype consisting of dilated cardiomyopathy, obsessive-compulsive disorders, and suicidality. [provided by RefSeq, Mar 2012]
