The FOXD2 Polyclonal Antibody (PAC017888) is a valuable tool for researchers studying FOXD2, a transcription factor involved in various biological processes, including development, cell differentiation, and cancer progression. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the FOXD2 protein, allowing for precise detection and analysis in a variety of cell types, making it an essential component in studies related to gene expression and regulation.FOXD2 is known for its role in controlling gene expression and modulating cellular functions, making it a key target for investigations into developmental disorders, cancer biology, and other disease states.
Understanding the mechanisms by which FOXD2 regulates gene transcription and cellular processes is essential for exploring potential therapeutic strategies that target FOXD2 in the treatment of various diseases. The FOXD2 Polyclonal Antibody is a valuable tool for researchers looking to delve deeper into the functions and significance of FOXD2 in biological pathways.
Antibody Name:
FOXD2 Antibody (PACO17888)
Antibody SKU:
PACO17888
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:15-1:50
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human FOXD2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain cancer tissue using PACO17888(FOXD2 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. FOX (Forkhead box) proteins are a family of transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity. Many FOX proteins are important to embryonic development.
Synonyms:
forkhead box D2
UniProt Protein Function:
FOXD2: Probable transcription factor involved in embryogenesis and somatogenesis.Protein type: DNA-binding; Cell development/differentiation; Transcription factorChromosomal Location of Human Ortholog: 1p34-p32Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; transcription factor activityBiological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
UniProt Protein Details:
NCBI Summary:
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined. [provided by RefSeq, Jul 2008]
