The FOXC1 Polyclonal Antibody (CAB2924) is designed for research involving FOXC1, a transcription factor that plays a key role in embryonic development and cell differentiation. The antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications including Western blot and immunohistochemistry.FOXC1 is known to regulate the expression of genes involved in important cellular processes such as cell proliferation, migration, and apoptosis. Dysregulation of FOXC1 has been linked to a variety of diseases, including cancer and developmental disorders.
Studying the expression and function of FOXC1 using this antibody can provide valuable insights into its role in these conditions.With its high reactivity and specificity, the FOXC1 Polyclonal Antibody is an essential tool for researchers working in the fields of molecular biology, developmental biology, and cancer research. By enabling the detection and analysis of FOXC1 protein in various cell types and tissues, this antibody facilitates the investigation of FOXC1's function and potential as a therapeutic target.
Product Name:
FOXC1 Rabbit Polyclonal Antibody
SKU:
CAB2924
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 404-553 of human FOXC1 (NP_001444.2).
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
Purification Method:
Affinity purification
Gene ID:
2296
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FOXC1 antibody (CAB2924) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
