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Formyl-HIST1H2BC (K108) Antibody (PACO65129)

SKU:
PACO65129
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
ICC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
€319
Frequently bought together:

Description

Formyl-HIST1H2BC (K108) Antibody (PACO65129)

The Formyl Hist1H2BC (K108) Antibody (PAC065129) is a valuable tool for researchers studying histone proteins and their post-translational modifications. Histones play a crucial role in packaging and regulating DNA within the nucleus, and modifications such as formylation can impact gene expression and chromatin structure.This highly specific antibody, generated in rabbits, is designed for use in various applications including Western blotting and immunohistochemistry. It recognizes the histone H2BC protein when modified at lysine 108, allowing for the detection and analysis of this specific modification in diverse cell types and experimental settings.

Studies have shown that formylation of histone proteins can influence DNA repair, transcriptional regulation, and other cellular processes. By utilizing the Formyl Hist1H2BC (K108) Antibody in your research, you can gain valuable insights into the role of histone modifications in health and disease, particularly in the fields of epigenetics, cancer biology, and developmental biology.

Product Name:Formyl-HIST1H2BC (K108) Antibody
Product Code:PACO65129
Size:50µL
Target Names:HIST1H2BC
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, ICC; Recommended dilution: ICC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (104-115aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK
Uniprot ID:P62807
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area:Epigenetics and Nuclear Signaling

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