FOLR1 Rabbit Polyclonal Antibody (CAB15672)
- SKU:
- CAB15672
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | FOLR1 Rabbit Polyclonal Antibody |
SKU: | CAB15672 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Folate Binding Protein(FBP) / FOLR1 (NP_000793.1). |
Sequence: | MAQR MTTQ LLLL LVWV AVVG EAQT RIAW ARTE LLNV CMNA KHHK EKPG PEDK LHEQ CRPW RKNA CCST NTSQ EAHK DVSY LYRF NWNH CGEM APAC KRHF |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | FBP; FOLR; NCFTD; FRalpha; Folate Binding Protein(FBP) / FOLR1 |
Positive Sample: | Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Apical cell membrane, Cell membrane, Cytoplasmic vesicle, Endosome, GPI-anchor, Lipid-anchor, Secreted, clathrin-coated vesicle. |
Calculated MW: | 30kDa |
Observed MW: | 37kDa |
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2348 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |