Folate Binding Protein (FBP) / FOLR1 Rabbit Monoclonal Antibody (CAB22481)
The Folate Binding Protein (FBP, FOLR1) Rabbit Monoclonal Antibody is a cutting-edge tool for researchers studying FBP, a key protein involved in regulating cell growth and division. This antibody, developed in rabbits, is highly specific and binds specifically to the FBP protein in human samples, allowing for precise detection and analysis in a variety of cell types.FBP, also known as FOLR1, plays a crucial role in the transportation of folate into cells, making it essential for DNA synthesis and cell proliferation. Dysregulation of FBP has been linked to various diseases, including cancer and folate deficiency disorders.
Understanding the function of FBP is vital for developing targeted therapies and diagnostic tools for these conditions.The Folate Binding Protein (FBP, FOLR1) Rabbit Monoclonal Antibody is validated for use in Western blot applications, providing researchers with a reliable tool for studying the expression and function of FBP. Its high specificity and sensitivity make it ideal for research in oncology, reproductive health, and drug development. Unlock the potential of FBP research with this innovative antibody.
Product Name:
Folate Binding Protein (FBP) / FOLR1 Rabbit Monoclonal Antibody
SKU:
CAB22481
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Folate Binding Protein(FBP) / FOLR1 (NP_000793.1).
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2348
Clone Number:
ARC50859_ARC50863
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts from HeLa cells, using Folate Binding Protein(FBP) / FOLR1 Rabbit PolymAb® (CAB22481) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
