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Folate Binding Protein (FBP) / FOLR1 Rabbit Monoclonal Antibody (CAB22481)

SKU:
CAB22481
€139
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Description

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Product Name:Folate Binding Protein (FBP) / FOLR1 Rabbit Monoclonal Antibody
SKU:CAB22481
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Folate Binding Protein(FBP) / FOLR1 (NP_000793.1).
Sequence:MAQR MTTQ LLLL LVWV AVVG EAQT RIAW ARTE LLNV CMNA KHHK EKPG PEDK LHEQ CRPW RKNA CCST NTSQ EAHK DVSY LYRF NWNH CGEM APAC KRHF
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:FBP; FOLR; NCFTD; FRalpha
Positive Sample:HeLa,Mouse kidney,Rat kidney
Conjugate:Unconjugated
Cellular Localization:Apical cell membrane, Cell membrane, Cytoplasmic vesicle, Endosome, GPI-anchor, Lipid-anchor, Secreted, clathrin-coated vesicle.
Calculated MW:30kDa
Observed MW:38kDa

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

Purification Method:Affinity purification
Gene ID:2348
Clone Number:ARC50859_ARC50863
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts from HeLa cells, using Folate Binding Protein(FBP) / FOLR1 Rabbit PolymAb® (CAB22481) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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