The FNTA Polyclonal Antibody (CAB8805) is a valuable tool for researchers studying FNTA, a crucial enzyme involved in protein prenylation, a key post-translational modification process. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for Western blot applications. By binding to the FNTA protein, it enables accurate detection and analysis in various cell types, making it ideal for investigations in biochemistry and drug discovery.FNTA plays a significant role in regulating the activity of small GTPases, which are essential for cellular signaling and proliferation processes.
Dysregulation of FNTA has been implicated in various diseases, including cancer and neurodegenerative disorders. Therefore, studying the function of FNTA is crucial for developing targeted therapies that can modulate protein prenylation and signaling pathways associated with disease progression.Overall, the FNTA Polyclonal Antibody (CAB8805) offers researchers a reliable tool for investigating the role of FNTA in cellular processes and disease pathogenesis, paving the way for potential therapeutic interventions targeting FNTA-mediated signaling pathways.
Product Name:
FNTA Rabbit Polyclonal Antibody
SKU:
CAB8805
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 280-379 of human FNTA (NP_002018.1).
cytoplasm, cytosol, plasma membrane, protein farnesyltransferase complex
Calculated MW:
44kDa
Observed MW:
44kDa
Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13.
Purification Method:
Affinity purification
Gene ID:
2339
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FNTA antibody (CAB8805) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
