Anti-FNDC5 Antibody (CAB18107)
- SKU:
- CAB18107
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Anti-FNDC5 Antibody (CAB18107)
The FNDC5 Polyclonal Antibody (CAB18107) is a valuable tool for researchers studying FNDC5, a protein known for its role in regulating metabolism and promoting exercise-induced benefits. This antibody, produced in rabbits, has been shown to be highly specific for human samples and is optimized for use in Western blot applications.FNDC5, also known as irisin, is a hormone-like protein released during exercise that has been associated with various health benefits, including improved glucose metabolism and increased energy expenditure.
Research into FNDC5 has implications for understanding metabolic disorders, obesity, and muscle physiology.By utilizing the FNDC5 Polyclonal Antibody, researchers can accurately detect and analyze FNDC5 protein levels in different cell types and tissues, providing valuable insights into its function and potential therapeutic applications. This antibody is a valuable tool for studies in metabolism, exercise physiology, and related fields of research.
| Antibody Name: | Anti-FNDC5 Antibody |
| Antibody SKU: | CAB18107 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human FNDC5. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | rat brain, rat heart |
| Immunogen: | Recombinant protein of human FNDC5. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 252995 |
| Uniprot: | Q8NAU1 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 23kDa |
 | Western blot - FNDC5 Polyclonal Antibody (CAB18107) |
| Synonyms: | FRCP2, irisin, FNDC5 |
| Background: |
| UniProt Protein Function: | FNDC5: Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 1p35.1 Cellular Component: endoplasmic reticulum; extracellular region; plasma membrane Biological Process: response to muscle activity |
| NCBI Summary: | This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] |
| UniProt Code: | Q8NAU1 |
| NCBI GenInfo Identifier: | 403314395 |
| NCBI Gene ID: | 252995 |
| NCBI Accession: | Q8NAU1.3 |
| UniProt Secondary Accession: | Q8NAU1,Q6P6D9, Q7Z676, A6NMC9, D3DPQ6, |
| UniProt Related Accession: | Q8NAU1 |
| Molecular Weight: | 23659 Da |
| NCBI Full Name: | Fibronectin type III domain-containing protein 5 |
| NCBI Synonym Full Names: | fibronectin type III domain containing 5 |
| NCBI Official Symbol: | FNDC5Â Â |
| NCBI Official Synonym Symbols: | FRCP2; irisin  |
| NCBI Protein Information: | fibronectin type III domain-containing protein 5 |
| UniProt Protein Name: | Fibronectin type III domain-containing protein 5 |
| UniProt Synonym Protein Names: | Fibronectin type III repeat-containing protein 2 |
| Protein Family: | Fibronectin type III domain-containing protein |
| UniProt Gene Name: | FNDC5Â Â |
| UniProt Entry Name: | FNDC5_HUMAN |
Related Products
Biotinylated Anti-FNDC5 PAb (KPAB0364)
