The FN3KRP Polyclonal Antibody (CAB15512) is a valuable tool for researchers studying FN3KRP, a key enzyme involved in fructosamine metabolism. This antibody, generated in rabbits, is highly specific to human FN3KRP and has been validated for use in Western blot applications. By binding to the FN3KRP protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential reagent for investigations into carbohydrate metabolism and related diseases.FN3KRP is a crucial player in the regulation of fructosamine levels, which are implicated in a range of metabolic disorders including diabetes and cardiovascular disease.
By studying the function and activity of FN3KRP, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets. The FN3KRP Polyclonal Antibody is a powerful tool for advancing our understanding of fructosamine metabolism and its role in human health.
Product Name:
FN3KRP Rabbit Polyclonal Antibody
SKU:
CAB15512
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human FN3KRP (NP_078895.2).
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
79672
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FN3KRP Rabbit pAb (CAB15512) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
